COSEQUIN DS provides the raw materials which are essential for the synthesis of synovial fluid as well as the complete cartilage matrix, including collagen, hyaluronic acid, and the various modified sugar chains of the glycosaminoglycans.
Unlike steroids and some NSAIDs which can damage chondrocytes, COSEQUIN DS is not a drug: it is a true, safe, nutraceutical.
COSEQUIN DS is a patented combination of glucosamine, purified chondroitin sulfate and manganese ascorbate. Each component has its own essential primary function in connective tissue synthesis.
Glucosamine hydrochloride - stimulates synthesis of synovial fluid and the complete cartilage matrix, including collagen and proteoglycans.
Chondroitin sulfate - in addition to being the major glycosaminoglycan (GAG) found in cartilage, it provides protection by inhibiting degradative enzymes. Manganese - must be present
in adequate amounts for proteoglycan biosynthesis to occur.
The synergistic effects of all components working concurrently is what makes COSEQUIN DS unique.
Cartilage replenishes its major components by manufacturing and remodelling collagen and proteoglycans. This constant and ongoing synthesising process often generates extremely large demands for the basic building blocks of both collagen and proteoglycans. If the raw materials are not available in the amounts required, at the time they are required, this synthesis process is impaired, and the ability to replenish itself is reduced.
COSEQUIN DS (Double Strength Sprinkle Capsules for Dogs) is a patented combination, where each capsule contains:
Glucosamine Hydrochloride 500 mg
Sodium Chondroitin Sulphate 400 mg
Also contains Manganese Gluconate & Calcium Ascorbate
Dosage and Administration
COSEQUIN DS is designed for daily supplementation.
The initial administration period is 4 - 6 weeks. The dosage may be increased, but should not be decreased during this period. Most dogs will respond during this time. The capsules are designed to be opened and sprinkled onto the food.
Initial 4 - 6 weeks (Loading Dose):
5 to 10 kg: 1/2 capsule morning and evening
11 - 22 kg: 1 capsule morning and evening
23 - 44 kg: 2 capsules morning plus 1 capsule evening
over 45 kg: 2 capsules morning and evening
After initial 4 - 6 weeks, reduce the number of capsules by 1/2 to 1 capsule (depending on size of pet) until the most economical (low) level that will keep the animal comfortable is found. This may commonly be 1 capsule daily (or 1/2 capsule daily for small dogs or cats). Administration may be increased at any time depending on the pet's needs.